HS-LS1-1: Proteins and Tissues

 

Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins which carry out the essential functions of life through systems of specialized cells.

 

Clarification Statement: none

Assessment Boundary: Assessment does not include identification of specific cell or tissue types, whole body systems, specific protein structures and functions, or the biochemistry of protein synthesis.

 

 

Lesson Plan

NGSS HS-LS1-1 focuses on understanding how genes encode for proteins, and how these proteins contribute to the structure and function of tissues within organisms. Here’s an aligned lesson plan:

Objective: Students will demonstrate an understanding of the relationship between genes, proteins, and tissues.

Materials:

  • Whiteboard or presentation tool
  • Models or diagrams of DNA, RNA, and protein synthesis
  • Images or examples of tissues in organisms
  • 3D MODELS

Introduction (10 mins):

  1. Review prior knowledge on DNA structure, genes, and proteins.
  2. Introduce the concept of tissues and their role in organisms' structure and function.

Main Body (25 mins):

  1. Explain the relationship between genes, proteins, and tissues: a. Emphasize that genes (specific sequences in DNA) contain instructions for making proteins. b. Describe how proteins contribute to the structure and function of tissues within organisms.

  2. Interactive Activity: a. Show models or diagrams of DNA, RNA, and protein synthesis. b. Engage students in a discussion or demonstration of how DNA serves as a template for mRNA, which in turn guides the formation of proteins.

  3. Tissues and Proteins: a. Show images or examples of different tissues in organisms (muscle, nerve, epithelial, etc.). b. Discuss specific proteins present in these tissues and how they contribute to the tissues' functions. c. Highlight the importance of proper protein structure in maintaining tissue integrity and function.

Conclusion (10 mins):

  1. Recap the main points: Genes contain instructions for making proteins, which contribute to the structure and function of tissues.
  2. Emphasize the interconnectedness between genes, proteins, and tissues in living organisms.
  3. Encourage students to consider real-world examples where disruptions in protein synthesis may impact tissue function or cause disorders.

Assessment:

  • Group Activity: Divide students into groups and provide scenarios where mutations in specific genes result in changes in protein structure and affect tissue function. Ask each group to discuss and present their understanding of the consequences.

Extensions:

  • Research Project: Assign students to investigate a specific tissue in the human body, identify key proteins present in that tissue, and explain their roles in maintaining tissue structure and function.
  • Case Studies: Explore case studies or articles about genetic disorders related to protein synthesis and tissue function, discussing their impact on individuals.

Teacher Notes

  1. Engage through Discussion: Start the lesson by engaging students in a discussion about their understanding of DNA, genes, and proteins. Encourage questions and elicit examples from everyday life that demonstrate the roles of proteins in tissues.

  2. Use Visual Aids: Utilize visual aids such as diagrams, animations, or models to illustrate the processes of DNA transcription, translation, and protein synthesis. Visual representation can greatly aid in understanding abstract concepts.

  3. Connect to Real-world Examples: Relate the concept of genes, proteins, and tissues to real-world examples or current scientific research. Highlight diseases or conditions caused by mutations affecting protein structure and tissue function.

  4. Encourage Group Activities: Break students into groups for activities that simulate protein synthesis or discuss scenarios where gene mutations impact tissue function. Encourage collaboration and peer learning during these activities.

  5. Differentiate Learning: Adapt the lesson for diverse learning styles and abilities. Provide additional resources or differentiated tasks for advanced learners and offer support for struggling students.

  6. Highlight Interdisciplinary Connections: Emphasize how knowledge of genes, proteins, and tissues connects with other scientific disciplines like biochemistry, physiology, and genetics. Show how this understanding is crucial in various fields such as medicine and biotechnology.

  7. Encourage Critical Thinking: Prompt students to think critically about the implications of disruptions in protein synthesis on tissues, and discuss potential solutions or therapies for genetic disorders affecting tissue function.

  8. Assessment Strategies: Use formative assessment tools during the lesson, such as discussions, quizzes, or group presentations, to gauge understanding. The exit ticket can serve as a summative assessment to evaluate individual comprehension.

  9. Provide Resources: Offer additional reading materials, websites, or videos for students who want to explore the topic further or who might need supplementary resources for better comprehension.

  10. Feedback and Reflection: After the lesson, provide constructive feedback to students based on their participation and understanding. Encourage reflection on the connections they made between genes, proteins, and tissues.

Adapting these teacher notes to suit the classroom dynamics and the students' level of understanding can help in delivering an engaging and informative lesson on the relationship between genes, proteins, and tissues according to NGSS HS-LS1-1 standards.

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